2004 Publications

Biomedical

Refereed journal articles and proceedings

Cogger VC, Muller M, Fraser R, McLean AJ & Le Couteur DG. The effects of tert-Bbutyl hydroperoxide on the hepatic sinusoid. Journal of Hepatology (In Press).

Cogger VC, Warren A, Fraser R, Ngu M, McLean AJ & Le Couteur DG. Preliminary analysis of the sinusoidal endothelium and space of Disse in ageing Papio hamadrayas. Comp Hepatol 14:S26;2004.

Driver C, Georgiou A & Georgiou G. The contribution by mitochondrially induced oxidative damage to aging in Drosophila melanogaster. Biogerontology 5:185-92;2004.

Fisher AA, Rubenach S, Davis MW, Le Couteur DG & McLean AJ. The epidemiology of hip fractures in the Australian Capital Territory. Osteoporosis International (In Press).

Hilmer SN, Warren A, Cogger VC, Fraser R, McLean AJ, Sullivan D & Le Couteur DG. The effect of aging on the immunohistochemistry of apolipoprotein E in the liver. Exp Gerontol 39:53-7;2004.

Khalil Z. Ageing neurovascular system as a therapeutic target in wound healing. Clinical and Experimental Pharmacology and Physiology 31:46;2004.

Khalil Z, Pearce AL, Storer E, Satkunanathan N, Finlay-Jones JJ & Hart PH. Regulation of wheal and flare by tea tree oil: complementary human and rodent studies. The J. Investigative Dermatology (In Press).

Le Couteur DG, Cogger VC, Hilmer SN, Muller M, Harris M, Sullivan D, McLean AJ & Fraser R. Aging, artherosclerosis and the liver sieve. Progress in Artherosclerosis Research (In Press).

Le Couteur DG, Fisher AA, Davis MW & McLean AJ. Cardiovascular responses to meals in the elderly: clinical and therapeutic implications. Age and Aging (In Press).

Le Couteur DG, Fraser R, Hilmer H, Rivory LP & McLean AJ. The haptic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance. Clinical Pharacokinetics (In Press).

Le Couteur DG, Yin ZL, McLean AJ & Rivory LP. Wash-in methodology and modelling to determine hepatocellular D-glucose transport in the perfused rat liver. Japanese Journal Physiology (In Press).

Livett BG, Gayler KR & Khalil Z. Drugs from the sea - conopeptides as potential therapeutics. Current Medicinal Chemistry 11:1711-9;2004.

McLean AJ & Le Couteur DG. Aging biology and geriatric clinical pharmacology. Pharmacological Reviews 56:163-84;2004.

Ogrin R, Darzins P & Khalil Z. Age-related changes in microvascular blood flow and transcutaneouse oxygen tension under basal and stimulated conditions. Journal of Gerontology (In press).

Abstracts

Doganay G & Khalil Z. Pharmacological manipulation of the vascular toxic effects of amyloid-beta peptides by Aricept and Exelon. 24th Annual Meeting, Australian Neuroscience Society, Melbourne 2004.

Khalil Z. Striking the balance between inflammation and pain to improve neuronal repair. ANS Satellite Meeing, "Understanding Pain-Biology to Behaviour", Melbourne 2004.

Khalil Z. Early diagnosis of dementia. Melbourne Health Research Week, Melbourne 2004.

Khalil Z. Improving tissue repair with age. Melbourne Health Research Week, Melbourne 2004.

Khalil Z, Khodr B, Gan B, Azar K & Darby I. A multi-antioxidant approach to improve sensory neurovascular function and tissue repair in advanced age. 24th Annual Meeting, Australian Neuroscience Society, Melbourne 2004.

Ogrin R, Khalil Z & Darzins P. Age-related changes in microvascular blood flow and transcutaneous oxygen tension under basal and stimulated conditions. Australian Wound Management Association 5th National Wound Healing Conference, Hobart 2004.

Satkunanathan N, Livett B, Gayler K, Sandall S, Down J & Khalil Z. A novel alpha-conotoxin Vc1.1 alleviates neuropathic pain. 24th Annual Meeting, Australian Neuroscience Society, Melbourne 2004.

Patents

Patent No: 2003904303 "nerve function and tissue healing" (Inventor: KHALIL Z) based on the use of a novel non-invasive sensory nerve stimulation technique to improve nerve function and accelerate wound repair in older adults. This patent is based on studies on sensory neurovascular function in aged rodents that were funded by NHMRC over 94-98 (basic research) and from 2002-2004 (clinical research).

Patent No: 2003905207 "Diagnostics" (Inventor: Khalil Z) based on the use of a novel skin test for early diagnosis of Alzheimer's Disease. This patent is based on studies on peripheral vascular actions of Beta amyloid protein that were funded by NHMRC over 94-98 (basic research) and from 2001-2003 (clinical research).

Australian patent application No PR4094 (provisional patent) "Analgesic Compound" University of Melbourne based on our molecular biology (RACE/PCR) conotoxin gene discovery approach and preliminary biological testing of CTX Vc1.1 in rats, was filed March 29, 2001 (Inventors: LIVETT BG, GAYLER KR, KHALIL Z, DOWN JG, SANDALL D and KEAYS D) and subsequently International Patent Application No. PCT/AU02/00411 filed on 28 March 2002 and designated all PCT member countries (published October 10, 2002).


Clinical

Chapters in books

Gibson SJ. Age differences in psychological factors related to pain perception and report. In S. J. Gibson and D. K. Wiener (Eds) Pain in older adults. Seattle, WA, IASP Publications. (In Press).

Gibson SJ & Chambers C. Pain over the life span: a developmental perspective. In T. Hadjistravopoulos and K. D. Craig (Eds) Pain: Psychological perspectives. Mahway, NJ, USA, Lawrence Erlbaum Associates Inc. Publishers. 2004.

Gibson SJ & Wiener DK. Pain in Older Adults. In E. Charlton (Eds) Core curriculum for professional education in pain, Seattle, WA, IASP Publications. (In Press).

Refereed journal articles and proceedings

Gibson SJ & Farrell M. What is different about pain in older people? Reviews in Analgesia (In Press).

Gibson SJ & Farrell MJ. A review of age differences in the neurophysiology of nociception and the perceptual experience of pain. Clinical Journal of Pain 20:227-39;2004.

Helme RD, Meliala A & Gibson SJ. Methodologic factors which contribute to variations in experimental pain threshold reported for older people. Neuroscience Letters 361:144-6;2004.

Abstracts

Garland K, Groves F, Arnold C, Mendelson G & Gibson SJ. The effect of a multidisciplinary pain management program in inducing change in chronic pain patients. The Australian Pain Society: 25th Annual Scientific Conference, Canberra 2004.

Gibson SJ, Benedetti F, Abbey J & Scherer S. Pain and dementia in residential care. The Australian Pain Society: 25th Annual Scientific Conference, Canberra 2004.

Gibson SJ, Groves F, Mendelson G & Arnold C. Age and gender differences in the clinical presentation of chronic pain patients. The Australian Pain Society: 25th Annual Scientific Conference, Canberra 2004.

Groves F, Gibson SJ, Arnold C & Mendelson G. An evaluation of anger, depression and anxiety as a type of general negative affect in chronic pain. The Australian Pain Society: 25th Annual Scientific Conference, Canberra 2004.

Theses

Kathryn Garland, PhD student, Psychology Department. "The chronic pain experience in Workers compensation patients and age matched controls." 2003.

Kimberley Hearne, BSc.(Hons), Department of Medicine. "Age differences in anxiety and pain: the role of primary afferent function." 2003.

Janet Maxwell, BBSc.(Hons), Psychology Department. "Pain sensitivity in Alzheimer's disease: sensory and affective components." 2003.

D Rosa BSc. (Hons), Department of Psychology. "Neural and vascular changes in response to familiar music in patients with Alzheimer's disease and in healthy older people." 2003.


Public Health

Chapters in books

Bernhardt J & Hill K. We only treat what it occurs to us to assess: The importance of knowledge based assessment. In K. Refshauge (Eds) Science based rehabilitation: Theories into practice. Oxford, Elsevier. (In Press).

Hill K & Murray K. Physical activity and falls prevention. In M. Morris and A. Schoo (Eds) Optimising physical activity, exercise and health in older people. Oxford, Elsevier Science Ltd. 2004.

Reports

Black K & Hill K. Evaluation of a minimum data set for Victorian Falls Clinics. Report to the DHS Acute and Sub-Acute Health Branch. Melbourne, 2004. Black K & Nankervis J. Priority of access: Training and trialing in the Northern Metropolitan region. Report to Northern Metropolitan Region Local Government HACC Services. Melbourne, 2004.

Bremner F. Outcome measurement for Victorian Continence Clinic services. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Bremner F. Service guidelines for Continence Clinic services. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Dow B, Black K & Bremner F. Evaluation of home-based rehabilitation in Victoria. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Dow B & Nankervis J. Report of phase 1 of the evaluation of the Southern Grampians and Glenelg rehabilitation program. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Engel, L., Lindner, H., & Hill, K. (2004). Taking steps to better health: Impact of using a pedometer on time spent walking in older adults with Type 2 diabetes. Melbourne, National Ageing Research Institute. 

Giummarra M, Black K, Haralambous B & Nankervis J. Literature Review: Achieving health promoting behaviour change among older people. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Haralambous B, Black K, Nankervis J & Giummarra M. Achieving health promotion behaviour change among older Victorians. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Haralambous B & Fearn M. Proceedings of Cognitive, Dementia and Memory Service (CDAMS) clinics workshops. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Haralambous B, Fearn M & Hill K. Barwon Health demonstration project: Rehabilitation volunteers (stroke); Final Report. Report to the Barwon Health Volunteer Service. Melbourne, 2004.

Hill K & Black K. Evaluation of a minimum data set for Victorian falls clinics. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Hill K, Fearn M & Lancaster M. Minimising the risk of falls and falls injuries: Guidelines for acute, sub-acute and residential care settings; Project Report. Report to the Victorian Quality Council. Melbourne, 2004.

Hill K, Hughes R, Kewish L & McDowell S. Stop a fall before a fall stops you. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Hill K, Vrantsidis F, Haralambous B, Fearn M, Smith R, Murray K, Sims J & Dorevitch M. An analysis of research on preventing falls and falls injury in older people: Community, residential care and hospital settings (2004 update). Report to the Australian Government Department of Health and Ageing. Canberra, 2004.

Hill K, Walsh W, Vu M, Black K, Blackberry I, Bailey K, Grieve J, Osborne D & Smith R. Avoiding the tumble: Falls prevention in the hospital setting. Report to the Department of Human Services (Victoria). Melbourne, 2004.

Refereed journal articles and proceedings

Black K, Osborne D & Lindeman M. Access to Local Government HACC services for people speaking a language other than English at home. Australian Journal of Primary Health 10:9-15;2004.

Darmadi-Blackberry I, Wahlqvist ML, Kouris-Blazos A, Steen B, Lukito W, Horie Y & Horie K. Legumes: the most important dietary predictor of survival in older people of different ethnicities. Asia Pac J Clin Nutr 13:217-20;2004.

Haines T, Bennell K, Osborne D & Hill K. Effectiveness of a targeted falls prevention program in a sub-acute hospital setting - a randomised controlled trial. British Medical Journal 328:676-9;2004. 

Hill K, Black K, Haines T, Walsh W & Vu M. Invited commentary - Falls prevention revisited: A call for a new approach (Dempsey). Journal of Clinical Nursing (In Press).

Hill K & Schwarz J. Clinical perspectives - Assessment and management of falls in older people. Internal Medicine Journal (In Press).

Hill K & Stinson A. A pilot study of falls, fear of falling, activity level and falls prevention actions in older people with polio. Aging: Clinical and Experimental Research. 16:126-31;2004.

Mackintosh S, Goldie P & Hill K. Falls incidence and factors associated with falling in older, community dwelling, stroke survivors and matched controls. Ageing: Clinical and Experimental Research. (In Press)

Mackintosh S, Hill K, Dodd K, Goldie P & Culham E. Falls and injury prevention should be part of every stroke rehabilitation plan. Clinical Rehabilitation (In Press).

Morris M, Osborne D, Hill K, Kendig H, Lundgren-Lindquist B & Reid J. Predisposing factors for occasional and multiple falls in older people who live at home. Australian Journal of Physiotherapy (In Press).

Abstracts

Gilbert J, Melbourne S, Blackberry I & Whiting R. Prescribing in older patients. RACP Annual Scientific Conference, Canberra 2004.

Nankervis J, Smith R, Stewart A & Black K. Well for Life - Promoting well being of older people in residential care services. 18th World Conference on Health Promotion and Health Education, Melbourne 2004.

Vrantisidis F, Russell M, Hill K & Fearn M. Falls prevention, physical activity and older people in residential aged care. 18th World Conference on Health Promotion and Health Education, Melbourne 2004.